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Laboratory of Modeling in Biology and Medicine

biophysics  ·  systems biology  ·  bioengineering

Head: Prof. Tomasz Lipniacki — institutional www e-mail: tlipnia@ippt.pan.pl or tomek@rice.edu phone: +48 22 8261281 ext. 409 room: 325

Recent publications of our Lab:

• Super-spreading events initiated the exponential growth phase of COVID-19 with R₀higher than initially estimated
  Kochańczyk M, Grabowski F, Lipniacki T
  Royal Society Open Science (2020) CrossRef | PDF SuppInfo Correspondence

• Quantitative determination of mechanical stability in the novel coro-navirus spike protein
  Moreira RA, Chwastyk M, Baker JL, Guzman HV, Poma AB
  Nanoscale 12:16409 (2020) CrossRef

• Ultraviolet light-assisted electrospinning of core–shell fully cross-linked P(NIPAAm-co-NIPMAAm) hydrogel-based nanofibers for thermally-induced drug delivery self-regulation
  Pawłowska S, Rinoldi C, Nakielski P, Ziai Y, Urbanek O, Li X, Kowalewski TA, Ding B, Pierini F.
  Advanced Materials Interfaces 2000247 (2020) CrossRef | SuppInfo-PDF SuppMovie-MP4 CoverPicture

• Accounting for corner flow unifies the understanding of droplet formation
  in microfluidic channels
  Korczyk PM, van Steijn V, Blonski S, Zaremba D, Beattie DA, Garstecki P.
  Nature Communications 10:2528 (2019) CrossRef | PDF SuppInfo-PDF
  

• The limited information capacity of cross-reactive sensors drives the evolutionary
  expansion of signaling
  Komorowski M, Tawfik DS.
  Cell Systems 8(1):76–85.e6 (2019) PubMed CrossRef
  

• Cell fate in antiviral response arises in the crosstalk of IRF, NF-κB and JAK/STAT pathways
  Czerkies M, Korwek Z, Prus W, Kochańczyk M, Jaruszewicz-Błońska J, Tudelska K, Błoński S, Kimmel M, Brasier AR, Lipniacki T.
  Nature Communications 9:493 (2018) PubMed CrossRef | PDF SuppInfo-PDF SuppData SuppMovies SuppCode
  

• An information-theoretic framework for deciphering pleiotropic and noisy
  biochemical signaling
  Jetka T, Nienałtowski K, Filippi S, Stumpf MPH, Komorowski M.
  Nature Communications 9:4591 (2018) PubMed CrossRef | PDF SuppInfo-PDF
  

• Single-material organic solar cells based on electrospun fullerene-grafted polythiophene nanofibers
  Pierini F, Lanzi M, Nakielski P, Pawłowska S, Urbanek O, Zembrzycki K, Kowalewski TA.
  Macromolecules 50(13):4972–81 (2017) CrossRef
  

• Traveling waves in a coupled reaction–diffusion and difference model of hematopoiesis
  Adimy M, Chekroun A, Kaźmierczak B.
  Journal of Differential Equations 262(7):4085–4128 (2017) CrossRef
  

• The propagation phenomenon of solutions of a parabolic problem on the sphere
  Kazmierczak B, Tsai J-C, Bialecki S.
  Mathematical Models and Methods in Applied Sciences 28(10):2001–2067 (2018) CrossRef

      → All publications

To learn more on our research, you may read our perspective on regulatory pathway modeling (a book chapter in Polish).