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From Laboratory of Modeling in Biology and Medicine
Laboratory of Modeling in Biology and Medicine
biophysics · systems biology · bioengineering
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Recent publications of our Lab (selected highlights):
- Nonself RNA rewires IFNβ signaling: A mathematical model of the innate immune response
Korwek Z, Czerkies M, Jaruszewicz-Błońska J, Prus W, Kosiuk I, Kochańczyk M, Lipniacki T
Science Signaling 16(815):eabq1173 (2023) CrossRef bioRxiv
- Antagonism between viral infection and innate immunity at the single-cell level
Grabowski F, Kochańczyk M, Korwek Z, Czerkies M, Prus W, Lipniacki T
PLOS Pathogens 19(9):e1011597 (2023) PubMed CrossRef | bioRxiv Code Data
- Concentration on demand – a microfluidic system for precise adjustment of the content of single droplets
Zaremba D, Błoński S, Korczyk PM
Chemical Engineering Journal 430(3):132935 (2022) CrossRef | PDF
- Molecular insights into receptor binding energetics and neutralization of SARS-CoV-2 variants
Koehler M, Ray A, Moreira RA, Juniku B, Poma AB, Alsteens D
Nature Communications 12(1):6977 (2021) CrossRef | PDF
- Direction of epithelial folding defines impact of mechanical forces on epithelial state,
Błoński S, J Aureille, S Badawi, D Zaremba, L Pernet, A Grichine, S Fraboulet, PM Korczyk, P Recho, Ch Guilluy, ME Dolega
Developmental Cell 56:3222–3234 (2021) CrossRef
- Fractional response analysis reveals logarithmic cytokine responses in cellular populations
Nienałtowski K, Rigby RE, Walczak J, Zakrzewska KE, Rehwinkel J, Komorowski M
Nature Communications 12:4175 (2021) CrossRef | PDF
- Super-spreading events initiated the exponential growth phase of COVID-19 with R0 higher than initially estimated
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Royal Society Open Science 7:200786 (2020) CrossRef | PDF SuppInfo-PDF Correspondence
- Quantitative determination of mechanical stability in the novel coronavirus spike protein
Moreira RA, Chwastyk M, Baker JL, Guzman HV, Poma AB
Nanoscale 12:16409 (2020) CrossRef
- Multifunctional platform based on electrospun nanofibers and plasmonic hydrogel: A smart nanostructured pillow for near-infrared light-driven biomedical applications
Nakielski P, Pawłowska S, Rinoldi C, Ziai Y, De Sio L, Urbanek O, Zembrzycki K, Pruchniewski M, Lanzi M, Salatelli E, Calogero A, Kowalewski TA, Yarin AL, Pierini F
ACS Applied Materials & Interfaces 12(49):54328–5434 (2020) CrossRef | PDF
- Ultraviolet light-assisted electrospinning of core–shell fully cross-linked P(NIPAAm-co-NIPMAAm) hydrogel-based nanofibers for thermally-induced drug delivery self-regulation
Pawłowska S, Rinoldi C, Nakielski P, Ziai Y, Urbanek O, Li X, Kowalewski TA, Ding B, Pierini F
Advanced Materials Interfaces 2000247 (2020) CrossRef | SuppInfo-PDF SuppMovie-MP4 CoverPicture
- Accounting for corner flow unifies the understanding of droplet formation
in microfluidic channels
Korczyk PM, van Steijn V, Blonski S, Zaremba D, Beattie DA, Garstecki P
Nature Communications 10:2528 (2019) CrossRef | PDF SuppInfo-PDF
- The limited information capacity of cross-reactive sensors drives the evolutionary
expansion of signaling
Komorowski M, Tawfik DS
Cell Systems 8(1):76–85.e6 (2019) PubMed CrossRef | PDF
- Cell fate in antiviral response arises in the crosstalk of IRF, NF-κB and JAK/STAT pathways
Czerkies M, Korwek Z, Prus W, Kochańczyk M, Jaruszewicz-Błońska J, Tudelska K, Błoński S, Kimmel M, Brasier AR, Lipniacki T
Nature Communications 9:493 (2018) PubMed CrossRef | PDF SuppInfo-PDF SuppData SuppMovies SuppCode
- An information-theoretic framework for deciphering pleiotropic and noisy
biochemical signaling
Jetka T, Nienałtowski K, Filippi S, Stumpf MPH, Komorowski M
Nature Communications 9:4591 (2018) PubMed CrossRef | PDF SuppInfo-PDF
- Single-material organic solar cells based on electrospun fullerene-grafted polythiophene nanofibers
Pierini F, Lanzi M, Nakielski P, Pawłowska S, Urbanek O, Zembrzycki K, Kowalewski TA
Macromolecules 50(13):4972–81 (2017) CrossRef
- Traveling waves in a coupled reaction–diffusion and difference model of hematopoiesis
Adimy M, Chekroun A, Kaźmierczak B
Journal of Differential Equations 262(7):4085–4128 (2017) CrossRef
To learn more on our research, you may read our perspective on regulatory pathway modeling (a book chapter in Polish).